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Co-administration of the HIV protease inhibitor saquinavir, a CYP3A4 inhibitor, at steady state (1200 mg three times a day) with sildenafil (one hundred viagra 100mg mg single dose) resulted in a a hundred and forty% increase in sildenafil Cmax and a 210% enhance in sildenafil AUC.
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Stop taking sildenafil and get medical help straight away if these results occur. He provides that other drugs can interact with sildenafil making them extra viagra ineffective or poisonous. Shabsigh R, Klein LT, Seidman S, Kaplan SA, Lehrhoff BJ, Ritter JS. Elevated incidence of depressive signs in males with erectile dysfunction.
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